A bus headed to Baton Rouge on Sunday morning carrying construction volunteers to aid in the flood relief effort crashed on Interstate 10 just after 7 a.m.
LA spokeswoman said the speeding bus lost control for unclear reasons. After hitting a fire truck and a Toyota Camry, the bus struck three firefighters who were responding to an earlier crash, throwing them over the guardrail of an elevated section of highway she added.
One firefighter died 36-year-old Spencer Chauvin, a fire chief from St. John the Baptist Parish.
The two other firefighters, William Mack, 35, and Nicholas Sale, 32, were hospitalized for various injuries along with 24 bus passengers.
The passenger in the Camry, 21-year-old died at the scene according to officials.
Louisiana State Police official said authorities plan to charge the bus driver, Denis Yasmire Amaya Rodriguez, 37, with two counts of negligent homicide, reckless operation and other crimes.
Rodriguez, A Honduran national, was in the country illegally and was driving without a license.